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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1449831Generated: November 3, 2026

Dimethylformamide → HCID 131719825, compound

https://huagongshe.com/reaction/1449831

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantBenzenemethanol, 4-amino-alpha-(aminomethyl)-3,5-dichloro-HCID 217242—
ReactantHCID 131719826HCID 131719826—
SolventEthyl acetate methanol triethylamineHCID 21980445—
ProductHCID 131719825HCID 131719825—

Reaction Steps

According to method I (dimethylformamide, 3 hours at 90° C.) from (12-bromo-1-dodecyl)2-nitrophenylacetate and 2-amino-1-(4-amino-3,5-dichlorophenyl)ethanol. Working up by means of chromatography (ethyl acetate/methanol/triethylamine 20:2:1). Recrystallized as the oxalate from acetone. Melting point: 67°-68° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05599966
Source datasetuspto-grants-1997_02
ORD IDord-e14fc99a45c04274aefac69e95812e2e
Source noteuspto-grants-1997_02