HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 131719827, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Benzenemethanol, 4-amino-alpha-(aminomethyl)-3,5-dichloro- | HCID 217242 | — |
| Reactant | HCID 54109772 | HCID 54109772 | — |
| Solvent | Ethyl acetate methanol triethylamine | HCID 21980445 | — |
| Product | HCID 131719827 | HCID 131719827 | — |
Reaction Steps
According to method I (dimethylformamide, 1 hour at 90° C.) from {2-(2-pyridyl)ethyl}6-bromohexanoate and 2-amino-1-(4-amino-3,5-dichlorophenyl)ethanol. Working up by means of chromatography (ethyl acetate/methanol/triethylamine 20:2:1). Recrystallized as the hemifumarate from acetone. Melting point: 75°-76° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05599966 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-dcda4681dff6451bb3b6ce0f25033c33 |
| Source note | uspto-grants-1997_02 |