4-Chloro-5-fluoro-2-propylpyridine → 3,4-Dichloro-5-fluoro-2-propyl-pyridine

HRID 1450069Notes

Reaction equation

HRID 1450069 reaction equation
[Cl:1]C1C(F)=CN=C(C)C=1.[Cl:10][C:11]1[C:16]([F:17])=[CH:15][N:14]=[C:13]([CH2:18][CH2:19][CH3:20])[CH:12]=1>>[Cl:1][C:12]1[C:13]([CH2:18][CH2:19][CH3:20])=[N:14][CH:15]=[C:16]([F:17])[C:11]=1[Cl:10]

Participants

3

Reactant 2

HCID 196912934-Chloro-5-fluoro-2-propylpyridine2×HCID 196914104-Chloro-5-fluoro-2-methylpyridine2×

Product 1

HCID 196912403,4-Dichloro-5-fluoro-2-propyl-pyridine

Procedure

By following the procedures described in Example 67 and replacing 4-chloro-5-fluoro-2-picoline (the product of Example 66) with 4-chloro-5-fluoro-2-propyl-pyridine (the product of Example 70), the title compound can be prepared.

Sources & evidence

ORD record
ord-6be3c37cf1b94826ac43a4832f2001b0
Source dataset
uspto-grants-1997_02
Patent number
US05599816

Reaction notes

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