HCID 131719066, compound → HCID 178465354, compound

HRID 1450179Notes

Reaction equation

HRID 1450179 reaction equation
[CH2:1]([NH:3][C:4]([NH:6][C@@H:7]([C:15]([N:17]1[CH2:34][CH2:33][CH2:32][C@H:18]1[C:19]([NH:21][C@H:22]([CH:30]=[O:31])[CH2:23][CH2:24][CH2:25][NH:26][C:27](=[NH:29])[NH2:28])=[O:20])=[O:16])[CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:5])[CH3:2].[ClH:35].O.C(NC(N[C@@H](C(N1CCC[C@H]1C(OCC1C=CC=CC=1)=O)=O)CC1C=CC=CC=1)=O)C>>[CH2:1]([NH:3][C:4]([NH:6][C@@H:7]([C:15]([N:17]1[CH2:34][CH2:33][CH2:32][C@H:18]1[C:19]([NH:21][C@H:22]([CH:30]=[O:31])[CH2:23][CH2:24][CH2:25][NH:26][C:27](=[NH:28])[NH2:29])=[O:20])=[O:16])[CH2:8][C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1)=[O:5])[CH3:2].[ClH:35]

Participants

3

Reactant 2

HCID 131719066HCID 131719066, compoundHCID 178465355HCID 178465355, compound

Product 1

HCID 178465354HCID 178465354, compound

Procedure

By methods substantially equivalent to those described in Example 1-D, 1-H and 1-I, 1.2 g of EtNHCO-D-Phe-Pro-Arg-H.HCl hydrate was prepared from EtNHCO-D-Phe-Pro-OBzl.

Sources & evidence

ORD record
ord-277832e832fc405682099a6ed7677df3
Source dataset
uspto-grants-1997_02
Patent number
US05602101

Reaction notes

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