HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl benzoylacetate → N-(6-methoxybenzothiazol-2-yl)-3-oxo-3-phenylpropanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl benzoylacetate | HCID 7170 | — |
| Reactant | 2-Amino-6-methoxybenzothiazole | HCID 15630 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | N-(6-methoxybenzothiazol-2-yl)-3-oxo-3-phenylpropanamide | HCID 19975336 | — |
Reaction Steps
Ethyl benzoyl acetate (9.5 ml) and 2-amino-6-methoxy benzothiazole (9.01 g) are heated to 140° under house vacuum for 2 hours. After cooling, the residue is taken up in acetone and filtered. The precipitate is dissolved in hot DMF to give an amide, N-(6-methoxybenzothiazol-2-yl)-3-oxo-3-phenylpropanamide (II).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05602115 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-d3cbfeb0ee684e0cb251a20883fea3aa |
| Source note | uspto-grants-1997_02 |