反应详情

A solution consisting of 2-methylcarbonylmethoxy-7-nitro-1,2,3,4-tetrahydroisoquinolin-1-one (500 mg, 1.9 mmol), 10% palladium on carbon (80 mg) and methanol (70 mL) was hydrogenated at 40 psi for 1 hour. The solution was filtered through Celite® and concentrated to give the title compound (400 mg, 90% yield).

1. filtrationThe solution was filtered through Celite®
2. concentrationconcentrated