N-Methylethylamine → 1-(benzo[d][1,3]dioxol-5-yl)-N-(5-((ethyl(methyl)amino)(2-methoxyphenyl)methyl)pyridin-2-yl)cyclopropanecarboxamide

HRID 145028Notes

Reaction equation

HRID 145028 reaction equation
[CH3:1][S:2]([O:3][CH:6]([c:7]1[c:8]([O:13][CH3:14])[cH:9][cH:10][cH:11][cH:12]1)[c:15]1[cH:16][n:17][c:18]([NH:21][C:22](=[O:23])[C:24]2([c:27]3[cH:28][c:29]4[c:30]([cH:34][cH:35]3)[O:31][CH2:32][O:33]4)[CH2:25][CH2:26]2)[cH:19][cH:20]1)(=[O:4])=[O:5].[CH3:36][NH:37][CH2:38][CH3:39].[O:40]1[c:41]2[cH:42][cH:43][c:44]([C:45]3([C:46]([NH:47][c:48]4[cH:49][cH:50][c:51]([CH:52]([N:53]([CH3:54])[CH3:55])[c:56]5[cH:57][cH:58][cH:59][cH:60][c:61]5[O:62][CH3:63])[cH:64][n:65]4)=[O:66])[CH2:67][CH2:68]3)[cH:69][c:70]2[O:71][CH2:72]1>>[CH:6]([c:7]1[c:8]([O:13][CH3:14])[cH:9][cH:10][cH:11][cH:12]1)([c:15]1[cH:16][n:17][c:18]([NH:21][C:22](=[O:23])[C:24]2([c:27]3[cH:28][c:29]4[c:30]([cH:34][cH:35]3)[O:31][CH2:32][O:33]4)[CH2:25][CH2:26]2)[cH:19][cH:20]1)[N:37]([CH3:36])[CH2:38][CH3:39]

Participants

4

Reactant 3

HCID 12219N-MethylethylamineHCID 442364971-(benzo[d][1,3]dioxol-5-yl)-N-(5-((dimethylamino)(2-methoxyphenyl)methyl)pyridin-2-yl)cyclopropanecarboxamideHCID 57895126(6-(1-(Benzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)pyridin-3-yl)(2-methoxyphenyl)methyl methanesulfonate

Product 1

HCID 578951651-(benzo[d][1,3]dioxol-5-yl)-N-(5-((ethyl(methyl)amino)(2-methoxyphenyl)methyl)pyridin-2-yl)cyclopropanecarboxamide

Sources & evidence

ORD record
ord-885faf3acf154e8fbc8fc185fc54d9ae
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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