HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropanol hydrochloride → trans-(+/-)-Tetrahydro-5-(phenoxymethyl)-3-furanthiol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropanol hydrochloride | HCID 21912024 | — |
| Reactant | Sodium methanolate methanol | HCID 23694274 | — |
| Reactant | Ethanethioic acid trans-(+/-)-S-[tetrahydro-5-(phenoxymethyl)-3-furanyl]-ester | HCID 86750316 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | trans-(+/-)-Tetrahydro-5-(phenoxymethyl)-3-furanthiol | HCID 86750315 | 70.1% |
Reaction Steps
The title compound is prepared by the procedure of Example 16 using 0.532 g of product from Example 23, 506 microliter of 25% sodium methoxide/methyl alcohol, 7.5 ml of tetrahydrofuran, and 1.18 ml of 1.86N hydrochloric acid/isopropyl alcohol to give 0.311 g of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05602118 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-02abfde5fe164a79b5244d31e1798f8c |
| Source note | uspto-grants-1997_02 |