HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium methanolate methanol → trans-(+/-)-5-[[(4-Fluorophenyl)sulfonyl]methyl]tetrahydro-3-furanthiol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium methanolate methanol | HCID 23694274 | — |
| Reactant | Ethanethioic acid trans-(+/-)-S-[5-[[(4-fluorophenyl)sulfonyl]methyl]tetrahydro-3-furanyl]ester | HCID 86750317 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | trans-(+/-)-5-[[(4-Fluorophenyl)sulfonyl]methyl]tetrahydro-3-furanthiol | HCID 86750319 | 63.1% |
Reaction Steps
The title compound is prepared by the procedure of Example 16 using 0.955 g of product from Example 31, 0.72 ml of 25% sodium methoxide/methyl alcohol and 10 ml of tetrahydrofuran to give 0.523 g of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05602118 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-16a447dd27174f948c2fd98de36566f0 |
| Source note | uspto-grants-1997_02 |