HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → (S)-2-[[[(4-Nitrophenyl)methoxy]carbonyl]amino]butanoic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | (-)-2-Aminobutyric acid | HCID 80283 | — |
| Reactant | Carbonic acid 4-Nitrophenyl (4-Nitrophenyl)methyl Ester | HCID 21829967 | — |
| Solvent | Water ethanol | HCID 19096565 | — |
| Product | (S)-2-[[[(4-Nitrophenyl)methoxy]carbonyl]amino]butanoic Acid | HCID 53667938 | 81.5% |
Reaction Steps
The title compound is prepared by the procedure of Example 255 using 29.46 g of product from Example 254, 9.5 g of L-2-aminobutyric acid, 25.5 ml of triethylamine and 1112 ml of 4:1 ethyl alcohol/water to give 21.2 g of the desired product after chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05602118 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-bcb972acd43a44b482f8449d31062f25 |
| Source note | uspto-grants-1997_02 |