HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → HCID 12336001, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Monobasic potassium phosphate | HCID 516951 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | HCID 53909053 | HCID 53909053 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 12336001 | HCID 12336001 | 80.5% |
Reaction Steps
A mixture of 0.56 g of product from Example 395, 0.60 ml of 4.37M sodium methoxide and 10 ml of tetrahydrofuran is stirred in an ice bath for 20 minutes. Ethyl acetate is added followed by 0.5M potassium phosphate monobasic. The organic layer is dried and concentrated in vacuo to give 0.37 g of the desired product as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05602118 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-177956d1e7df4dc18b0664f0414ad999 |
| Source note | uspto-grants-1997_02 |