HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 4'-[[2-n-Propyl-4-methyl-6-(imidazo[1,2-a]pyrimidin-2-yl)-benzimidazol-1-yl]-methyl]-biphenyl-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 19965039 | HCID 19965039 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4'-[[2-n-Propyl-4-methyl-6-(imidazo[1,2-a]pyrimidin-2-yl)-benzimidazol-1-yl]-methyl]-biphenyl-2-carboxylic acid | HCID 19964734 | — |
Reaction Steps
Prepared analogously to Example 1 from tert.-butyl 4'-[[2-n-propyl-4-methyl-6-(imidazo[1,2-a]pyrimidin-2-yl)-benzimidazol-1-yl]-methyl]-biphenyl-2-carboxylate and trifluoroacetic acid in methylene chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05602127 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-b586ff61313749afb4411f018d5e6f5a |
| Source note | uspto-grants-1997_02 |