Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1450572Generated: October 27, 2026

Trifluoroacetic acid → 4'-[(2-n-Propyl-4-methyl-6-(5,6,7,8-tetrahydro-imidazo[1,2-a]pyridin-2-yl)-benzimidazol-1-yl)-methyl]-biphenyl-2-carboxylic acid

https://huagongshe.com/reaction/1450572

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 67708446HCID 67708446—
SolventDichloromethaneHCID 6344—
Product4'-[(2-n-Propyl-4-methyl-6-(5,6,7,8-tetrahydro-imidazo[1,2-a]pyridin-2-yl)-benzimidazol-1-yl)-methyl]-biphenyl-2-carboxylic acidHCID 19964521—

Reaction Steps

Prepared analogously to Example 1 from tert.butyl 4'-[(2-n-propyl-4-methyl-6-(5,6,7,8-tetrahydro-imidazo-[1,2-a]pyridin-2-yl)-benzimidazol-1-yl)-methyl]-biphenyl-2-carboxylate and trifluoroacetic acid in methylene chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05602127
Source datasetuspto-grants-1997_02
ORD IDord-c4fea998a1204cdaaa7d65d4a516a09c
Source noteuspto-grants-1997_02