HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(2-(Dimethylamino)ethyl)formamide → 4'-[[2-n-Propyl-4-methyl-6-[1-(2-dimethylamino-ethyl)-4,5-dimethyl-imidazol-2-yl]-1H-benzimidazol-1-yl]-methyl]-biphenyl-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(2-(Dimethylamino)ethyl)formamide | HCID 245580 | — |
| Reactant | tert.butyl 4'-[[2-n-propyl-4-methyl-6-(4,5-dimethyl-oxazol-2-yl)-1H-benzimidazol-1-yl]-methyl]-biphenyl-2-carboxylate | HCID 67708414 | — |
| Product | 4'-[[2-n-Propyl-4-methyl-6-[1-(2-dimethylamino-ethyl)-4,5-dimethyl-imidazol-2-yl]-1H-benzimidazol-1-yl]-methyl]-biphenyl-2-carboxylic acid | HCID 19964825 | — |
Reaction Steps
Prepared analogously to Example 146 from tert.butyl 4'-[[2-n-propyl-4-methyl-6-(4,5-dimethyl-oxazol-2-yl)-1H-benzimidazol-1-yl]-methyl]-biphenyl-2-carboxylate and N-(2-dimethylaminoethyl)formamide/-2-dimethylamino-ethylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05602127 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-62ff067bf28d415a91e8f33e5ee74202 |
| Source note | uspto-grants-1997_02 |