HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 19358849, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4,6-Dichloro-5-nitropyrimidine | HCID 20312 | — |
| Reactant | Stannous Chloride | HCID 24479 | — |
| Reactant | 2-Ethylimidazole | HCID 66130 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | BENZYL-(1-METHYL-PIPERIDIN-4-YL)-AMINE | HCID 1114650 | — |
| Product | HCID 19358849 | HCID 19358849 | — |
Reaction Steps
Prepared by treatment of 4,6-dichloro-5-nitropyrimidine with 1-methyl-4-(benzylamino)piperidine, followed by reaction with 2-ethylimidazole, reduction with tin (II) chloride, cyclization with carbonyldiimidazole and debenzylation with refluxing 6N HCl for 30 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05602252 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-5b0afcd9295846bcbac72f5d16fef128 |
| Source note | uspto-grants-1997_02 |