反应详情

Methyl 4-(methylaminocarbonyl)benzoate (1.9 g, 0.0098 mol) was added to 10 mL 1.5M NaOH (1.5 eq) and 30 mL water in a 125-mL Erlenmeyer flask. The suspension was stirred for 1 h at room temperature. The solid gradually dissolved during this time. The solution was filtered and acidified to produce a white solid. The solid was removed by filtration, washed twice with water, and dried in vacuo to give 1.60 g (90%) of the title compound, mp 270° C.

1. dissolutionThe solid gradually dissolved during this time
2. filtrationThe solution was filtered
3. customto produce a white solid
4. customThe solid was removed by filtration
5. washwashed twice with water
6. customdried in vacuo