HCID 10613312, compound → HCID 10729899, compound

Participants

Reaction Steps

Ethyl 3-nitro-4-[(methylsulfonyl)amino]benzoate (1.0 g, 0.0035 mol) was dissolved in ethanol (40 mL) and hydrogenated at 20 psi in the presence of platinum oxide (Aldrich, 0.02 g) for 1 h. The catalyst was removed by filtration through Celite and the filtrate was concentrated to 20 mL. On cooling, a precipitate formed which was separated by filtration, washed with cold ethanol, and dried to give 0.75 g (84%) of ethyl 3-amino-4-[(methylsulfonyl)amino]benzoate as a white powder, mp 151° C.

Provenance & Evidence