Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 145122Generated: October 25, 2026

Hydrochloric Acid → 1,3-Dihydro-3-(RS)-(5-hydroxy-2-indolylcarbonyl)amino-5-(2-fluorophenyl)-2H-1,4-benzodiazepin-2-one

https://huagongshe.com/reaction/145122

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant5-Hydroxyindole-2-carboxylic acidHCID 88958—
Reactant1,3-dihydro-5-(2-fluorophenyl)-3-amino-2H-1,4-benzodiazepin-2-oneHCID 15637150—
Product1,3-Dihydro-3-(RS)-(5-hydroxy-2-indolylcarbonyl)amino-5-(2-fluorophenyl)-2H-1,4-benzodiazepin-2-oneHCID 14208234—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-7dc6bb37e952438bb89c5ef6cc6e5f60
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)