Sodium Perchlorate → HCID 178521652, compound

Participants

Reaction Steps

A mixture of 1-benzyl-2-(1,3-dioxolan-2-yl)-3-benzyl-imidazolium bromide (17.3 g) and 450 ml of 48% HBr was heated on an oil-bath (120°-130° C.) and stirred for 48 h. The mixture was concentrated in vacuo at 60° C. and the resulting green colored residue was redissolved in water. The aqueous solution was treated with a sodium perchlorate (2 equiv) solution and the precipitated product was separated by decanting, and crystallized from CH3CNEtOAC. The solid product was collected by filtration, washed with ethanol and dried in vacuo to afford 18.6 g of 1-benzylimidazo[1,2-b]isoquinolin-4-ium perchlorate (Formula II: A=1-benzylimidazole; R1 =R6 =H; X- =ClO4-).

Provenance & Evidence