HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → 3-Acetoxy-17-(3-pyridyl)estra-1,3,5[10],16-tetraene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 3-(Diethylboryl)pyridine | HCID 642851 | — |
| Reactant | HCID 10478617 | HCID 10478617 | — |
| Catalyst | HCID 178418476 | HCID 178418476 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-Acetoxy-17-(3-pyridyl)estra-1,3,5[10],16-tetraene | HCID 10339319 | — |
Reaction Steps
The method followed that described in Example 1(b), but using diethyl(3-pyridyl)borane (1.65 g, 11.2 mmol), 3-acetoxyestra-1,3,5[10],16-tetraen-17-yl trifluoromethanesulphonate (3.56 g, 8.0 mmol), THF (40 ml), bis(triphenylphosphine)palladium(II) chloride (56 mg, 0.08 mmol), and aqueous sodium carbonate (2M, 15 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05604213 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-7e8cb078504c4aefb1b167037ef64889 |
| Source note | uspto-grants-1997_02 |