HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl chloroacetate → 2-(2-Methyl-thiazol-4-yl)morpholin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl chloroacetate | HCID 7751 | — |
| Reactant | 2-Amino-1-(2-methyl-1,3-thiazol-4-yl)ethanol | HCID 16768496 | — |
| Solvent | Ethylacetate methanol | HCID 21584119 | — |
| Product | 2-(2-Methyl-thiazol-4-yl)morpholin-5-one | HCID 19974356 | — |
Reaction Steps
Prepared analogously to Example S by reaction of 2-hydroxy-2-(2-methyl-thiazol-4-yl)ethanamine with ethyl chloroacetate and purification on a silica gel column using ethyl acetate/methanol=19:1 as eluant.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05604225 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-71009529708849e9ab009638f9166887 |
| Source note | uspto-grants-1997_02 |