HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → HCID 19974326, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | HCID 10978660 | HCID 10978660 | — |
| Reactant | HCID 14347764 | HCID 14347764 | — |
| Product | HCID 19974326 | HCID 19974326 | — |
Reaction Steps
Prepared analogously to Example 3 by reaction of 2-trifluoromethyl-4-bromoacetyl-thiazole and N-(2-hydroxyethyl)-2-(4-carbomethoxymethoxyphenyl)-1-methylethylamine. Before the reduction with sodium borohydride, the mixture is heated to boiling for 3 hours to complete the reaction. The base is then purified on a silica gel column using ethyl acetate as mobile phase.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05604225 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-46b43cbf173b455c8a0489f2a7c70d88 |
| Source note | uspto-grants-1997_02 |