HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-Trifluoromethyl-thiazol-4-yl)morpholine → N-[2-(4-(2-Carbomethoxy-1-methylethenyl) phenyl)-1-methylethyl]-2-(2-trifluoromethyl-thiazol-4-yl)morpholine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-Trifluoromethyl-thiazol-4-yl)morpholine | HCID 19974265 | — |
| Reactant | 1-[4-(2-Carbomethoxy-1-methylethenyl)phenyl]propan-2-one | HCID 54548003 | — |
| Product | N-[2-(4-(2-Carbomethoxy-1-methylethenyl) phenyl)-1-methylethyl]-2-(2-trifluoromethyl-thiazol-4-yl)morpholine | HCID 54361252 | — |
Reaction Steps
Prepared analogously to Example 13 by reaction of 2-(2-trifluoromethyl-thiazol-4-yl)morpholine with 1-[4-(2-carbomethoxy-1-methylethenyl)phenyl]propan-2-one followed by purification of the base on a silica gel column using chloroform/ethyl acetate=19:1 as eluant.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05604225 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-31990047139541eca836fc5ad078e386 |
| Source note | uspto-grants-1997_02 |