HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-(2-Hydroxyethoxy)phenyl)propan-2-one → N-[2-(4-(2-Hydroxyethoxy)phenyl)-1-methylethyl]-2-hydroxy-2-(2-methyl-thiazol-4-yl)ethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-(2-Hydroxyethoxy)phenyl)propan-2-one | HCID 14578857 | — |
| Reactant | 2-Amino-1-(2-methyl-1,3-thiazol-4-yl)ethanol | HCID 16768496 | — |
| Product | N-[2-(4-(2-Hydroxyethoxy)phenyl)-1-methylethyl]-2-hydroxy-2-(2-methyl-thiazol-4-yl)ethanamine | HCID 14372870 | — |
Reaction Steps
Prepared by analogy to Example 13 by reaction of 2-hydroxy-2-(2-methyl-thiazol-4-yl)ethanamine with 1-[4-(2-hydroxyethoxy)phenyl)propan-2-one followed by purification on a silica gel column using methylene chloride/methanol=9:1 as eluant.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05604225 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-c07a081f633847fe8d7f68907d4a5676 |
| Source note | uspto-grants-1997_02 |