HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → HCID 54298386, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Acetic acid, 2-(triphenylphosphoranylidene)-, ethyl ester | HCID 70670 | — |
| Reactant | HCID 19974927 | HCID 19974927 | — |
| Product | HCID 54298386 | HCID 54298386 | — |
Reaction Steps
A mixture of the indole from Step 2 (8.46 g, 23.6 mmol) and (carbethoxymethylene)triphenylphosphorane (16.9 g, 48.6 mmol) was suspended in 25 mL of toluene and heated to reflux for 15 h. The solvent was removed in vacuo and the residue was purified by flash chromatography (25% ethyl acetate/hexanes) to provide 9.38 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05604253 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-a3ed86b9d21f46eb89e575d344680571 |
| Source note | uspto-grants-1997_02 |