Hydrochloric Acid → HCID 21849400, compound

Participants

Reaction Steps

2-Acetamido-l,3-diacetoxy-2-hexadecylpropane (1.75 g) was dissolved in 100 ml of methanol and 23.8 ml of a 1N aqueous sodium hydroxide solution was added thereto. The mixture was refluxed under heating for 6 hours. The mixture was neutralized with a 1N aqueous hydrochloric acid solution and concentrated under reduced pressure. The concentrate was washed with water and ethyl acetate:hexane =1:1 in order to give 892 mg of 2-amino-2-hexadecyl-1,3-propanediol hydrochloride.

Provenance & Evidence