HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 4-(3-Bromopropoxy)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | N-[4-(3-bromopropoxy)phenyl]acetamide | HCID 10849771 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 4-(3-Bromopropoxy)aniline | HCID 19974563 | — |
Reaction Steps
A mixture of the product of part (i) above (13 g) and 5N hydrochloric acid (200 ml) was heated under reflux for 2 h. After cooling, the mixture was basified with sodium hydroxide solution and extracted with dichloromethane. The organic phase was evaporated to give the title compound (7 g) as an oil. IR includes a peak at 3360-3450 cm-1 (NH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05604237 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-844f3f95de144ec39e3629178d3a957b |
| Source note | uspto-grants-1997_02 |