Phenyl isocyanate → 2-(phenylcarbamoyl)amino-5-[4,5-dihydropyridazin-3(2H)-on-6-yl]indane

HRID 1451776Notes

Reaction equation

HRID 1451776 reaction equation
[NH2:1][CH:2]1[CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:11]3[CH2:12][CH2:13][C:14](=[O:17])[NH:15][N:16]=3)[CH:8]=2)[CH2:3]1.[C:18]1([N:24]=[C:25]=[O:26])[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[C:18]1([NH:24][C:25]([NH:1][CH:2]2[CH2:10][C:9]3[C:4](=[CH:5][CH:6]=[C:7]([C:11]4[CH2:12][CH2:13][C:14](=[O:17])[NH:15][N:16]=4)[CH:8]=3)[CH2:3]2)=[O:26])[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 7672Phenyl isocyanateHCID 140714996-(2-amino-indan-5-yl)-4,5-dihydropyridazin-3(2H)-one

Product 1

HCID 194314732-(phenylcarbamoyl)amino-5-[4,5-dihydropyridazin-3(2H)-on-6-yl]indane

Procedure

2-Amino-5-[4,5-dihydropyridazin-3(2H)-on-6-yl]indane and phenyl isocyanate were treated in the same manner as in Example 29 to obtain 2-(phenylcarbamoyl) amino-5-[4,5-di-hydropyridazin-3(2H)-on-6-yl]indane.

Sources & evidence

ORD record
ord-343eebea0f3e40128d740f2c449c8fc4
Source dataset
uspto-grants-1997_02
Patent number
US05605901

Reaction notes

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