173019-82-4 → HCID 10715514, compound

HRID 1451823Notes

Reaction equation

HRID 1451823 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][CH:9]2[S:13][C:12](=[O:14])[NH:11][C:10]2=[O:15])=[CH:4][CH:3]=1.CC1C=CC=C(SC2SC(=O)NC2=O)C=1.[Cl:31][C:32]1[CH:37]=[CH:36][C:35]([C:38]#[C:39][CH2:40]Br)=[CH:34][CH:33]=1.FC1C=C(C#CCBr)C=C(F)C=1>>[Cl:31][C:32]1[CH:37]=[CH:36][C:35]([C:38]#[C:39][CH2:40][C:9]2([S:8][C:5]3[CH:4]=[CH:3][C:2]([F:1])=[CH:7][CH:6]=3)[S:13][C:12](=[O:14])[NH:11][C:10]2=[O:15])=[CH:34][CH:33]=1

Participants

5

Reactant 4

HCID 10513607173019-82-4HCID 10610046HCID 10610046, compoundHCID 10610242HCID 10610242, compoundHCID 19973049HCID 19973049, compound

Product 1

HCID 10715514HCID 10715514, compound

Procedure

Prepared from 5-(4-fluorophenyl-sulfanyl)-thiazolidine-2,4-dione of formula (III), Example 5 and [3-(4-chlorophenyl)-prop-2-ynyl]-bromide of formula (IX), from Example 21: mp 116°-117° C.; Anal. Calc. for C18H11ClFNO2S2 : C, 55.17; H, 2.83; N, 3.57; Found: C, 54.58; H, 2.65; N, 3.39.

Sources & evidence

ORD record
ord-57460d2e11d1447fb2b517079ed230d5
Source dataset
uspto-grants-1997_02
Patent number
US05605918

Reaction notes

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