HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 3-Chlorobenzene-1-sulfonyl isocyanate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 3-Chlorobenzenesulfonamide | HCID 519377 | — |
| Solvent | 1,2-Dichlorobenzene | HCID 7239 | — |
| Product | 3-Chlorobenzene-1-sulfonyl isocyanate | HCID 19973470 | 40% |
Reaction Steps
5,7-Dichloro-4-[3-chlorobenzenesulfonimide]-1,4-dihydroquinoline-2-carboxylic acid, methyl ester ##STR30## Combine oxalyl chloride (25mL) and 3-chlorobenzenesulfonamide (4.3g, 23mmol) and reflux overnight. Remove oxalyl chloride in vacuo and combine the resulting residue with o-dichlorobenzene (25mL) and reflux. Evaporate the solvent in vacuo to distill to give [3-chlorobenzenesulfonyl]isocyanate (2g, 40%); bp 92°-5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05606063 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-8e13e076709544fbbd917889406f0e01 |
| Source note | uspto-grants-1997_02 |