Hydrochloric Acid → HCID 22145372, compound

Participants

Reaction Steps

3-Acetyl-1-(2-t-butyldimethylsilyloxyethyl)-5-methylpyrazole (1.6 g, 5.7 mM) in methanol (50 ml) was treated with 2M hydrochloric acid (10 ml). After stirring for 0.5 h the mixture was evaporated to remove methanol and the residual oil extracted repeatedly with dichloromethane and ethyl acetate to give the title compound as a colouless oil (0.633 g, 66%); δH (CDCl3) 2.30 (3H, s), 2.48 (3H, s), 3.98-4.09 (2H, m), 4.12-4.21 (2H, m), and 6.49 (1H, s).

Provenance & Evidence