Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethyl Sulfoxide → [(4-Ethenylphenyl)methyl](methyl)propanedinitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethyl Sulfoxide | HCID 679 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | p-Vinylbenzyl chloride | HCID 74126 | — |
| 반응물 | Propanedinitrile,2-methyl- | HCID 57349445 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | [(4-Ethenylphenyl)methyl](methyl)propanedinitrile | HCID 71402933 | 64% |
반응 단계
A sample (2.53 g) of triethylamine (25 mmol) was added dropwise to a mixture of 4.01 g 4-vinylbenzyl chloride (25 mmol), 2.00 g monomethyl malonitrile (25 mmol), and 15 mL DMSO at room temperature. The mixture was stirred at room temperature for 17 hours then poured into 100 mL water. A pink solid precipitated and was filtered. The solid was recrystallized from a mixture of methanol and water to give 3.141 g (64%) of pinkish crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07473652B2 |
| 출처 데이터셋 | uspto-grants-2009_01 |
| ORD ID | ord-439c0858f674420d99d9f0612054fb20 |
| 출처 메모 | uspto-grants-2009_01 |