HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous Chloride → 3-Fluoro-4-(4-methyl-[1,2,3]triazol-1-yl)-phenylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous Chloride | HCID 24479 | — |
| Reactant | 1-(2-Fluoro-4-nitro-phenyl)-4-methyl-[1,2,3]-triazole | HCID 57526988 | — |
| Product | 3-Fluoro-4-(4-methyl-[1,2,3]triazol-1-yl)-phenylamine | HCID 57526989 | 95.9% |
Reaction Steps
1-(2-Fluoro-4-nitro-phenyl)-4-methyl-[1,2,3]-triazole (Intermediate 22) (38.3 g, 0.173 mol) and SnCl2 2H2O (200 g, 0.886 mol) were reacted as described for Intermediate 27 to give the crude title compound as a off-white solid (31.9 g), which was used directly for the next reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07473699B2 |
| Source dataset | uspto-grants-2009_01 |
| ORD ID | ord-0d0248ec50214d13bce37fbc45e37923 |
| Source note | uspto-grants-2009_01 |