Methanol → HCID 10093954, compound

Participants

Reaction Steps

(5R)-3-[4-(Tetrahydro-2H-thiopyran-4-yl)-3,5-difluorophenyl]-5 [(4-methyl-1,2,3-triazol-1-yl)methyl]oxazolidin-2-one (Example 24) (0.5 g, 1.27 mmol) was oxidized with 3-chloro perbenzoic acid (0.94 g, 3.8 mmol) as described for Intermediate 2. Chromatography on silica gel with 0-10% methanol in dichloromethane gave the title compound as as colourless solid (0.54 g).

Provenance & Evidence