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HRID1452835

反应详情

EQUATION

反应方程式

HRID 1452835 的结构方程式

REACTANTS

反应物

2
结构：C[Si](C)(C)I
HCID85247

Silane, iodotrimethyl-

C3H9ISi

结构：Cc1nn(C(=O)OC(C)(C)C)c2ccc(NS(=O)(=O)c3ccccc3S(C)(=O)=O)cc12
HCID22567145

1,1-Dimethylethyl 3-methyl-5-[[[2-(methylsulfonyl)phenyl]sulfonyl]amino]-1H-indazole-1-carboxylate

C20H23N3O6S2

PRODUCTS

生成物

1
结构：Cc1n[nH]c2ccc(NS(=O)(=O)c3ccccc3S(C)(=O)=O)cc12
HCID178434305

未命名化合物

收率 30.8%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClC(Cl)Cl
溶剂HCID6212

Chloroform

CHCl3

PROCEDURE

实验过程

2-Methylsulfonyl-N-(3-methyl-1H-indazol-5-yl)benzenesulfonamide can be obtained as described in Example 6 from 1.45 g of N-(N-tert-butoxycarbonyl-3-methyl-1H-indazol-5-yl)-2-methylsulfonylbenzenesulfonamide, 12.6 ml of chloroform and 0.44 ml of iodotrimethylsilane. 0.35 g of 2-methylsulfonyl-N-(3-methyl-1H-indazol-5-yl)benzenesulfonamide is thus obtained in the form of a white solid melting above 260° C. (analysis: C15H15N3O4S2 % calculated C, 49.30; H, 4.14; N, 11.50; O, 17.51; S, 17.55. % found C, 48.99; H, 4.45; N, 11.67; S, 17.23).