HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Fluorobenzenesulfonyl Chloride → 3-fluoro-N-(3-methylsulfonylamino-1H-indazol-5-yl)benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Fluorobenzenesulfonyl Chloride | HCID 2734258 | — |
| Reactant | 5-amino-3-methylsulfonylamino-1H-indazole | HCID 22567284 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 3-fluoro-N-(3-methylsulfonylamino-1H-indazol-5-yl)benzenesulfonamide | HCID 22567191 | 18.3% |
Reaction Steps
3-Fluoro-N-(3-methylsulfonylamino-1H-indazol-5-yl)benzenesulfonamide can be obtained as described in Example 2 from 0.1 g of 5-amino-3-methylsulfonylamino-1H-indazole, 5 ml of pyridine and 83 mg of 3-fluorobenzenesulfonyl chloride. 30 mg of 3-fluoro-N-(3-methylsulfonylamino-1H-indazol-5-yl)benzenesulfonamide are thus obtained in the form of a beige solid melting at 230° C. (analysis C14H13FN4O4S2.0.57H2O % calculated C, 43.75; H, 3.41; F, 4.94; N, 14.57; O, 16.65; S, 16.68. % found C, 43.75; H, 2.86; N, 14.77; S, 15.93).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07473701B2 |
| Source dataset | uspto-grants-2009_01 |
| ORD ID | ord-448e487458c34f4f8cfd62d48333c180 |
| Source note | uspto-grants-2009_01 |