化工社化工社 化学情報印刷レポート · 研究参考用
Ammonia → 5-amino-3-methylsulfonylamino-1H-indazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ammonia | HCID 222 | — |
| 反応物 | Ethanol | HCID 702 | — |
| 反応物 | 3-methylsulfonylamino-5-nitro-1H-indazole | HCID 22567201 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 5-amino-3-methylsulfonylamino-1H-indazole | HCID 22567284 | 44.2% |
反応手順
5-Amino-3-methylsulfonylamino-1H-indazole can be obtained as described in Example 4 from 256 mg of 3-methylsulfonylamino-5-nitro-1H-indazole, 10 ml of ethanol, 2 g of ferrous sulfate, 3.2 ml of water and 2.4 ml of 32% aqueous ammonia. 0.1 g of 5-amino-3-methylsulfonylamino-1H-indazole is thus obtained in the form of an oil used as it is in the following step.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07473701B2 |
| 出典データセット | uspto-grants-2009_01 |
| ORD ID | ord-f321f5f43589499298e470735efc4ddf |
| 出典メモ | uspto-grants-2009_01 |