HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → N-[5-(3,5-difluorobenzenesulfonylamino)-1H-indazol-3-yl)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | N-(3-amino-1H-indazol-5-yl)-3,5-difluorobenzenesulfonamide | HCID 22567125 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | N-[5-(3,5-difluorobenzenesulfonylamino)-1H-indazol-3-yl)-acetamide | HCID 22567091 | — |
Reaction Steps
N-[5-(3,5-Difluorobenzenesulfonylamino)-1H-indazol-3-yl]acetamide can be obtained as described in Example 28 from 0.1 g of N-(3-amino-1H-indazol-5-yl)-3,5-difluorobenzenesulfonamide, 9 ml of pyridine and 0.024 ml of acetyl chloride. 338 mg of N-[5-(3,5-difluorobenzenesulfonylamino)-1H-indazol-3-yl)-acetamide are thus obtained in the form of a cream solid melting at 268° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07473701B2 |
| Source dataset | uspto-grants-2009_01 |
| ORD ID | ord-54bfaa38a1ad4f6abb76452a6aee2105 |
| Source note | uspto-grants-2009_01 |