HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Aminobenzo[d]thiazol-6-yl)methanol → 2-Aminobenzo[d]thiazole-6-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Aminobenzo[d]thiazol-6-yl)methanol | HCID 13821540 | — |
| Catalyst | Manganese dioxide | HCID 14801 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-Aminobenzo[d]thiazole-6-carbaldehyde | HCID 13821541 | 87.6% |
Reaction Steps
To a solution of (2-aminobenzo[d]thiazol-6-yl)methanol (1.90 g, 10.5 mmol, 1.0 eq.) in THF (75 mL) under nitrogen was added MnO2 (14 g, 161 mmol, 15.3 eq.). After stirring overnight, the reaction solution was filtered through Celite and rinsed with THF. The filtrate was concentrated in vacuo to give 2-aminobenzo[d]thiazole-6-carbaldehyde as a yellow solid (1.64 g, 87% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07473784B2 |
| Source dataset | uspto-grants-2009_01 |
| ORD ID | ord-d4c0a27c61424dd3a69e0b8ac9cbdd38 |
| Source note | uspto-grants-2009_01 |