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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1452946Generated: October 27, 2026

(2-Aminobenzo[d]thiazol-6-yl)methanol → 2-Aminobenzo[d]thiazole-6-carbaldehyde

https://huagongshe.com/reaction/1452946

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Aminobenzo[d]thiazol-6-yl)methanolHCID 13821540—
CatalystManganese dioxideHCID 14801—
SolventTetrahydrofuranHCID 8028—
Product2-Aminobenzo[d]thiazole-6-carbaldehydeHCID 1382154187.6%

Reaction Steps

To a solution of (2-aminobenzo[d]thiazol-6-yl)methanol (1.90 g, 10.5 mmol, 1.0 eq.) in THF (75 mL) under nitrogen was added MnO2 (14 g, 161 mmol, 15.3 eq.). After stirring overnight, the reaction solution was filtered through Celite and rinsed with THF. The filtrate was concentrated in vacuo to give 2-aminobenzo[d]thiazole-6-carbaldehyde as a yellow solid (1.64 g, 87% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07473784B2
Source datasetuspto-grants-2009_01
ORD IDord-d4c0a27c61424dd3a69e0b8ac9cbdd38
Source noteuspto-grants-2009_01