Cyclohexanepropanoic acid → 5-Cyclohexyl-1-cyclopentyl-pentan-1-one

HRID 1453269Notes

Reaction equation

HRID 1453269 reaction equation
[CH:1]1([CH2:7][CH2:8][CH2:9][CH2:10][C:11]([OH:13])=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH:14]1([CH2:20][CH2:21][C:22](O)=O)[CH2:19]CCCC1>>[CH:1]1([CH2:7][CH2:8][CH2:9][CH2:10][C:11]([CH:19]2[CH2:14][CH2:20][CH2:21][CH2:22]2)=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 69702Cyclohexanepropanoic acidHCID 94769Cyclohexanepentanoic acid

Product 1

HCID 587624865-Cyclohexyl-1-cyclopentyl-pentan-1-one

Procedure

The title compound was prepared analogously to Example A(44), where cyclohexanepentanoic acid was substituted in place of 3-cyclohexylpropionic acid in Step 1 of that example. 1H NMR (DMSO-d6): δ 0.79-0.91 (m, 2H), 1.11-1.85 (m, 23H), 2.40 (t, J=7, 2H), 2.8-2.90 (m, 1H).

Sources & evidence

ORD record
ord-a62e5918a9614f69a7a652f759800522
Source dataset
uspto-grants-2009_01
Patent number
US07473790B2

Reaction notes

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