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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1453300Generated: October 25, 2026

2,3-Dichlorobenzenethiol → 6-[2-(3-chloro-4-methoxyphenyl)ethyl]6-cyclopentyl-3-[(2,3-dichlorophenyl)thio]4-hydroxy-5,6-dihydro-2H-pyran-2-one

https://huagongshe.com/reaction/1453300

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-DichlorobenzenethiolHCID 140202—
Reactant3-Chloro-6-[2-(3-chloro-4-methoxy-phenyl)-ethyl]-6-cyclopentyl-dihydro-pyran-2,4-dioneHCID 68867451—
Product6-[2-(3-chloro-4-methoxyphenyl)ethyl]6-cyclopentyl-3-[(2,3-dichlorophenyl)thio]4-hydroxy-5,6-dihydro-2H-pyran-2-oneHCID 58762572—

Reaction Steps

The title compound was prepared as described in Example C(70), where 3-chloro-6-[2-(3-chloro-4-methoxyphenyl)ethyl]-6-cyclopentyldihydro-2H-pyran-2,4(3H)-dione was used in place of 3-chloro-6-[2-(5-chloro-2,4-dimethoxyphenyl)ethyl]6-cyclopentyldihydro-2H-pyran-2,4(3H)-dione and 2,3-dichlorothiophenol was used in place of 6-hydroxy-8-mercaptopurine monohydrate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07473790B2
Source datasetuspto-grants-2009_01
ORD IDord-0a6760c8948c469f9c3ddff86c8f24a1
Source noteuspto-grants-2009_01