[2-(2-Cyclopentyl-4,6-dioxo-tetrahydro-pyran-2-yl)-ethyl]-carbamic Acid Tert-Butyl Ester → HCID 68867536, compound

HRID 1453334Notes

Reaction equation

HRID 1453334 reaction equation
C(OC(=O)[NH:7][CH2:8][CH2:9][C:10]1([CH:18]2[CH2:22][CH2:21][CH2:20][CH2:19]2)[CH2:15][C:14](=[O:16])[CH2:13][C:12](=[O:17])[O:11]1)(C)(C)C>C(O)(C(F)(F)F)=O.C(Cl)Cl>[NH2:7][CH2:8][CH2:9][C:10]1([CH:18]2[CH2:22][CH2:21][CH2:20][CH2:19]2)[O:11][C:12](=[O:17])[CH2:13][C:14](=[O:16])[CH2:15]1

Participants

3

Reactant 1

HCID 58762283[2-(2-Cyclopentyl-4,6-dioxo-tetrahydro-pyran-2-yl)-ethyl]-carbamic Acid Tert-Butyl Ester

Product 1

HCID 68867536HCID 68867536, compound

Reagents, catalysts & solvents 1

HCID 21863450Trifluoroacetic acid methylene chlorideSolvent

Procedure

A solution of [2-(2-cyclopentyl-4,6-dioxo-tetrahydro-pyran-2-yl)-ethyl]-carbamic acid tert-butyl ester (1.0 g, 2.8 mmol) from Step 4 above in 10% TFA/CH2Cl2 was stirred at room temperature for 20 minutes. The reaction was concentrated by rotary evaporation and used as is without further purification.

Workup

  1. concentrationThe reaction was concentrated by rotary evaporation
  2. customas is without further purification

Sources & evidence

ORD record
ord-c653667e15ed44a39a966140994d7fce
Source dataset
uspto-grants-2009_01
Patent number
US07473790B2

Reaction notes

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