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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1453420Generated: October 26, 2026

1,3-Benzodioxole-5-carboxylic acid → (R)-N-(1-hydroxy-4-methylpentan-2-yl)benzo[d][1,3]dioxole-5-carboxamide

https://huagongshe.com/reaction/1453420

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-Benzodioxole-5-carboxylic acidHCID 7196—
Reactant(R)-aminoleucinolHCID 86597565—
Product(R)-N-(1-hydroxy-4-methylpentan-2-yl)benzo[d][1,3]dioxole-5-carboxamideHCID 39364600—

Reaction Steps

Prepared in a similar manner to example 4 using benzo[d][1,3]dioxole-5-carboxylic acid and (R)-aminoleucinol. MS (M+H, 266.1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07476399B2
Source datasetuspto-grants-2009_01
ORD IDord-10cd2f97b8d3498db4d679946bda40c1
Source noteuspto-grants-2009_01