4-Heptanamine → N-(heptan-4-yl)benzofuran-5-carboxamide
Reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([OH:12])=O)=[CH:9][C:4]=2[CH:3]=[CH:2]1.[CH3:13][CH2:14][CH2:15][CH:16]([NH2:20])[CH2:17][CH2:18][CH3:19]>>[CH3:13][CH2:14][CH2:15][CH:16]([NH:20][C:10]([C:8]1[CH:7]=[CH:6][C:5]2[O:1][CH:2]=[CH:3][C:4]=2[CH:9]=1)=[O:12])[CH2:17][CH2:18][CH3:19]Participants
3
Procedure
Prepared in a similar manner to example 4 using benzofuran-5-carboxylic acid and heptan-4-amine. Yield 41%. MS (M+H, 260.2).
Sources & evidence
- ORD record
- ord-3946c7ea68454e03b4f00f953327571b
- Source dataset
- uspto-grants-2009_01
- Patent number
- US07476399B2
Reaction notes
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