4-Heptanamine → HCID 57528021, compound

HRID 1453485Notes

Reaction equation

HRID 1453485 reaction equation
[C:1]([C:3]1[CH:11]=[C:10]([O:12][CH3:13])[CH:9]=[CH:8][C:4]=1[C:5]([OH:7])=O)#[N:2].[CH3:14][CH2:15][CH2:16][CH:17]([NH2:21])[CH2:18][CH2:19][CH3:20]>>[C:1]([C:3]1[CH:11]=[C:10]([O:12][CH3:13])[CH:9]=[CH:8][C:4]=1[C:5]([NH:21][CH:17]([CH2:18][CH2:19][CH3:20])[CH2:16][CH2:15][CH3:14])=[O:7])#[N:2]

Participants

3

Reactant 2

HCID 386654-HeptanamineHCID 667730152-cyano-4-methoxybenzoic acid

Product 1

HCID 57528021HCID 57528021, compoundYield 73%

Procedure

Prepared in a similar manner to example 4 using 2-cyano-4-methoxybenzoic acid and 4-Heptylamine. Yield: 73%. 1H NMR (CD3OD): δ0.94 (t, 6H, J=7.3 Hz), 1.38 (m, 4H), 1.53 (m, 4H), 4.02 (s, 3H),4.12 (m, 1H), 7.27 (d, 1H, J=9.40 Hz), 8.11 (d, 2H, J=2.21 Hz). MS (M+H, 275).

Sources & evidence

ORD record
ord-32e5d665e7304a01a46390d9ed7a2a4d
Source dataset
uspto-grants-2009_01
Patent number
US07476399B2

Reaction notes

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