HuagongsheHuagongshe Chemistry Print Report · For research reference only
D-Leucine, methyl ester → (R)-methyl 2-(2,3-dimethylfuran-5-carboxamido)-4-methylpentanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | D-Leucine, methyl ester | HCID 89967 | — |
| Reactant | 4,5-Dimethylfuran-2-carboxylic acid | HCID 2774924 | — |
| Product | (R)-methyl 2-(2,3-dimethylfuran-5-carboxamido)-4-methylpentanoate | HCID 57527841 | 27% |
Reaction Steps
Prepared in a similar manner to example 4 using 4,5-dimethyl-furan-2-carboxylic acid and D-leucine methyl ester. Yield: 27%. 1H NMR (500 MHz, CDCl3): δ 0.96 (t, 6H), 1.66 (m, 3H), 1.96 (s, 3H), 2.26 (s, 3H), 3.75 (s, 3H), 4.78 (m, 1H), 6.51 (d, 1H), 6.89 (s, 1H). MS (M+H, 268).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07476399B2 |
| Source dataset | uspto-grants-2009_01 |
| ORD ID | ord-261ac68051e640dc93f79867e8781cf4 |
| Source note | uspto-grants-2009_01 |