(R)-1-(4-Methoxyphenyl)ethylamine → 4-Methoxy-N-[1-(R)-(4-methoxy-phenyl)-ethyl]-3-methyl-benzamide

HRID 1453500Notes

Reaction equation

HRID 1453500 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=O)=[CH:5][C:4]=1[CH3:12].[CH3:13][O:14][C:15]1[CH:20]=[CH:19][C:18]([C@H:21]([NH2:23])[CH3:22])=[CH:17][CH:16]=1>>[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([NH:23][C@@H:21]([C:18]2[CH:19]=[CH:20][C:15]([O:14][CH3:13])=[CH:16][CH:17]=2)[CH3:22])=[O:9])=[CH:5][C:4]=1[CH3:12]

Participants

3

Reactant 2

HCID 641449(R)-1-(4-Methoxyphenyl)ethylamineHCID 27595834-Methoxy-3-methylbenzoic Acid

Product 1

HCID 285582324-Methoxy-N-[1-(R)-(4-methoxy-phenyl)-ethyl]-3-methyl-benzamide

Procedure

Prepared in a similar manner to example 4 using 4-methoxy-3-methyl-benzoic acid and 1-(R)-(4-methoxy-phenyl)-ethylamine. MS (M+H, 300.1).

Sources & evidence

ORD record
ord-5307abb7e78c4ce285bed9cc73fdf1d9
Source dataset
uspto-grants-2009_01
Patent number
US07476399B2

Reaction notes

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