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HRID1453514

反应详情

EQUATION

反应方程式

HRID 1453514 的结构方程式

REACTANTS

反应物

2
结构：Cc1c(F)c(F)c(C(=O)O)c(F)c1F
HCID69548

2,3,5,6-Tetrafluoro-4-methylbenzoic acid

C8H4F4O2

结构：CC(C)[C@H](C)N
HCID6999788

(S)-(+)-3-Methyl-2-butylamine

C5H13N

PRODUCTS

生成物

1
结构：Cc1c(F)c(F)c(C(=O)N[C@@H](C)C(C)C)c(F)c1F
HCID57527834

未命名化合物

PROCEDURE

实验过程

Prepared in a similar manner to Example 162 using (S)-3-methylbutan-2-amine and 2,3,5,6-tetrafluoro-p-toluic acid acid (93%). 1H NMR (CDCl3) δ 0.98 (d, J=6.9 Hz, 6H) 1.18 (d, J=6.8 Hz, 3H), 2.29 (m, 3H), 4.09 (m, 1H), 5.72 (bs, 1H). MS (304.1, M+H) m.p. 146-147° C.