Hydrochloric Acid → HCID 72714301, compound

Participants

Reaction Conditions

Reaction Steps

100 mg of the compound obtained in Step A above are dissolved in 4 ml of isopropanol. The mixture is heated to 60° C., then 200 mg of sodium borohydride are added. After minutes at that temperature, the solvent is evaporated off under reduced pressure. The residue that is obtained is taken up in 10 ml of water, cooled in an ice bath and adjusted to pH 4 by addition of 6N hydrochloric acid. The insoluble material is collected by filtration and washed with water. The product is then dissolved in a minimum of chloroform and precipitated by addition of n-hexane. The precipitate is then collected by filtration.

Provenance & Evidence