HCID 178422320, compound → HCID 178422322, compound

HRID 1453554Notes

Reaction equation

HRID 1453554 reaction equation
[NH2:1][C@H:2]1[CH2:7][CH2:6][C@H:5]([NH2:8])[CH2:4][CH2:3]1.Cl[C:10]1[N:18]=[C:17]2[C:13]([N:14]=[CH:15][NH:16]2)=[C:12]([N:19]2[C:23]3[CH:24]=[C:25]([CH3:29])[C:26]([CH3:28])=[CH:27][C:22]=3[N:21]=[CH:20]2)[N:11]=1>>[CH3:28][C:26]1[C:25]([CH3:29])=[CH:24][C:23]2[N:19]([C:12]3[N:11]=[C:10]([NH:1][C@H:2]4[CH2:7][CH2:6][C@H:5]([NH2:8])[CH2:4][CH2:3]4)[N:18]=[C:17]4[C:13]=3[N:14]=[CH:15][NH:16]4)[CH:20]=[N:21][C:22]=2[CH:27]=1

Participants

3

Reactant 2

HCID 178422320HCID 178422320, compoundHCID 178511674HCID 178511674, compound

Product 1

HCID 178422322HCID 178422322, compound

Conditions

Temperature
140 °C

Procedure

570 mg of trans-1,4-diaminocyclohexane are brought to its melting temperature (70° C.), 149 mg of product obtained in stage 1 above are added in a single step, and the mixture is then heated at 140° C. for approximately 18 hours.

Workup

  1. additionabove are added in a single step

Sources & evidence

ORD record
ord-99681b4b70cf4affb24e5bd685e9b140
Source dataset
uspto-grants-2009_01
Patent number
US07476670B2

Reaction notes

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